Explaining the Endocannabinoid System

Updated: Apr 8

Maintaining healthy relationships plays a vital role in the quality of our lives. From how much daily activity we do, to putting healthy foods into our bodies, to how we physically feel, there are numerous variables that play a factor in our overall health and wellbeing.


This is also true about our body, which has numerous life-essential regulatory systems. One in particular is based on biochemical relationships that help our bodies maintain equilibrium, the Endocannabinoid System.


What is the Endocannabinoid System (ECS)?


The ECS was discovered in the 1960s and 1970’s, when scientists were researching the effects of cannabis on the human body. The ECS is a network of endocannabinoid and cannabinoid receptors that exist throughout our bodies. It plays a critical part in the development of the central nervous system and exists in your body even if you do not use cannabis.


Cannabinoid receptors are found on the surface of cells and listen to conditions outside of the cell and transmit information about changing conditions to the inside of the cell, thus kick-starting the appropriate cellular response. Endocannabinoids are small molecules that activate cannabinoid receptors. Endocannabinoids are found in the immune system, the central nervous system, the brain, organs, connective tissue, and glands.


What does the ECS do?

The ECS allows your body to maintain homeostasis, by monitoring what is going on in your body and stabilizing your body’s internal environment. Homeostasis refers to the regulation of conditions in the body, providing your body with internal stability, despite fluctuations in your external environment. Researchers have linked the ECS to many physiological processes such as sleep, chronic pain, inflammation, mood, appetite, digestion, memory, metabolism, liver function, and more.


The ECS has a series of receptors on cells throughout the body that accept cannabinoids, like CBD in Sustainable CBD’s products. The two main receptors are CB1 and CB2 and receive two different types of cannabinoids:

  • Endocannabinoids – The cannabinoids our body makes

  • Phytocannabinoids – Natural plant cannabinoids

CB1 is found mainly in the brain and central nervous system. Activation of this receptor is being studied for its therapeutic value of neurodegenerative diseases and neuropsychological disorders.


CB2 is expressed throughout the body’s immune system and is being researched for the receptor’s immune responses and involvement in moderating inflammation.


How Does CBD fit into the ECS?


Instead of binding directly with our cannabinoid receptors, CBD has an indirect influence on the ECS. CBD can help your body produce more endocannabinoids naturally, which results in a better functioning ECS and an overall healthier body. When you take Sustainable CBD oil or use any of our other CBD products, you are absorbing CBD into your bloodstream, allowing it to interact with your ECS. If your ECS is not working properly or struggling to maintain homeostasis, CBD may provide it with the much-needed boost to realign itself. Researchers continue to understand how CBD interacts with the human body’s ECS, but scientists believe that the ECS is an important system in the human body that will help us further understand the impact CBD has on our bodies.

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